Why Getting a Flu Shot Matters for Heart Health

Why Getting a Flu Shot Matters for Heart Health

Why Getting a Flu Shot Matters for Heart Health
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With few exceptions, health experts recommend that everyone — from 6-month-old babies to adults in their sixties and well beyond — get a flu shot every fall. Vaccination can help prevent or lessen the severity of illness by lowering the chance of serious complications, such as hospitalization, respiratory failure, pneumonia, or heart attack.

The advice for an annual flu shot is especially vital for anyone at high risk for cardiovascular problems. “This includes people over 65, as well as those with a history of heart disease, stroke, or risk factors for cardiovascular disease like smoking and diabetes,” says Eduardo Sanchez, MD, MPH, chief medical officer for prevention for the American Heart Association.

Even so, people in this high-risk group often skip their annual flu shot. If this applies to you, it’s important to understand how the influenza vaccine can protect your health. It may even save your life.

Why Getting a Flu Shot Matters for Heart Health

Even people without a history of heart disease or heart issues are at a higher risk of developing either after getting the flu.

Research has found that after being diagnosed with the flu, adults are 76 percent more likely to develop heart issues than those not diagnosed with the flu. Compared with people who don’t get the flu, those who are infected are 6 times more likely to have a heart attack (when blood flow to the heart is blocked) in the week following flu diagnosis. Again, older adults and people with a history of heart disease are most at risk.

Cardiac health is especially vulnerable during the flu because of a cascade of events triggered by the infection.

For one, infection-related inflammation elevates blood pressure, which stresses the heart and requires it to work much harder. In people with existing heart disease or a history of heart problems, this strains the already vulnerable cardiovascular system.

Also, in people with cardiovascular risk factors, inflammation in the lining of the arteries can contribute to the formation of arterial plaques (waxy substances that can cause blockages) and coronary heart disease, says Joyce Oen-Hsiao, MD, a cardiologist and associate professor of medicine at Yale University School of Medicine in New Haven, Connecticut. “If there are already cholesterol plaques on the arteries, the increased inflammation can increase the chance that the plaque will rupture, potentially causing a heart attack,” she says.

Additionally, research suggests that the virus and the subsequent inflammation can damage cells in the inner lining of blood vessels (endothelium), disrupting blood flow. The flu virus can even infect the heart itself, directly damaging cells.

“In very bad cases of the flu, when the body is trying to fight off the virus, there is a risk of direct inflammation of the heart (myocarditis), which can lead to a decrease in heart function and even heart failure,” Dr. Oen-Hsiao says.

Research shows that pneumonia, a common flu complication, can cause further inflammation-related damage to the heart and blood vessels, potentially leading to increased plaque formation and blockages.

Getting vaccinated can help significantly lower the risk of major flu-related cardiac complications — including heart attacks, severe heart failure, transient ischemic stroke, and even death — in high-risk groups. In people with existing heart disease specifically, getting the flu vaccine can reduce the risk of a major cardiac event by 30 to 50 percent, according to a research review.

Even if you’re vaccinated and still get the flu, the symptoms will likely be milder, says Siqin Ye, MD, a cardiologist and associate professor of medicine at Columbia University Vagelos College of Physicians and Surgeons in New York City. “So this is still very helpful for patients with existing cardiovascular disease. A milder flu episode is less likely to worsen heart conditions.”

The benefits of the flu shot may be especially prominent for people who’ve recently had a heart attack.

Research on recent heart attack survivors showed that getting vaccinated lowered their risk of a second heart-related event by 45 percent.

5 Tips for Making Your Flu Shot Count

Flu vaccines are considered safe for most everyone, including people with heart disease. The following can help you make the most of yours.

1. Timing Is Everything

Flu season starts to gear up in the fall and peaks between December and February. It takes a couple of weeks after vaccination for immunity to set in, so it’s ideal to get a flu shot before then (especially for people with heart disease or risk factors). An easy way to think about it, Dr. Sanchez says, is to make Halloween — October 31 — your deadline.

2. But It’s Never Too Late

Even if you miss that deadline, get a shot anyway. Flu season can linger into late spring, so getting vaccinated in November or even later can still help protect you from the virus. In fact, Sanchez says, if you got the flu early in the season, it’s not too late to get vaccinated to prevent a second bout of illness.

And remember, if you have heart disease or risk factors, the vaccine can help reduce your risk of serious complications, including atherosclerosis (plaque buildup in the arteries), stroke, heart attack, and heart failure.

3. Make Sure You’re Healthy

“A runny nose or sore throat shouldn’t stop you from getting a flu vaccine,” Sanchez says. It’s also okay to get the flu vaccine if you’ve recently been treated for a heart condition, Dr. Ye says. “In fact, we often recommend flu and pneumonia vaccinations for patients who are about to be discharged from a hospitalization for cardiovascular conditions.”

However, if you have a fever, it’s best to wait, as a high temperature means your immune system is focused on fighting off an infection.

Staying home until severe infections have passed also helps prevent the spread of infection to others.

4. Be Picky, if Possible

All flu shots are approved by the U.S. Food and Drug Administration, even those offered at your local supermarket pharmacy or pop-up vaccination clinic, meaning they’re safe and effective. However, since older adults are at an increased risk of serious flu complications, including heart-related ones, the Centers for Disease Control and Prevention recommends that people 65 and over get either a high-dose flu vaccine (Fluzone high dose or Flublock recombinant) or an adjuvanted one, which has an added ingredient to help it boost the immune response. If neither is available, get whichever flu shot is; it will still provide plenty of protection.

Bear in mind that the nasal spray generally isn’t recommended for people with heart disease or a history of stroke, though the shot is okay.

5. Stay Up to Date on Other Vaccines

If you’re due for another vaccine, including a COVID-19 shot or booster, or a pneumococcal vaccine, it’s absolutely fine to roll up both sleeves at the same time as you get a flu shot. Pneumonia is a common complication of the flu.

You may also be eligible for an RSV vaccine if you’re in a high-risk group, such as being 75 or older or in your third trimester of pregnancy. It’s safe to get this shot at the same time as others, as well.

EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
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Cheng-Han Chen

Cheng-Han Chen, MD, PhD, FACC, FSCAI

Medical Reviewer

Cheng-Han Chen, MD, PhD, is the medical director of the structural heart program at MemorialCare Saddleback Medical Center in Laguna Hills, California, and director of structural a...

Michelle Konstantinovsky

Michelle Konstantinovsky

Author
Michelle Konstantinovsky is a Bay Area–based freelance journalist, marketing specialist, and ghostwriter. An alumnus of the University of California in Berkeley Graduate School of ...