What to Know About a Suspected Death From Pneumonic Plague
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What to Know About a Suspected Death From Pneumonic Plague

Pneumonic plague is a rare but potentially lethal infection most commonly caused by flea-borne bacteria.
What to Know About a Suspected Death From Pneumonic Plague
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Public health experts across the globe are on alert following reports of a suspected lab leak at a plague research facility in Russia. A 28-year-old scientist who worked there died from double pneumonia (affecting both lungs), and unconfirmed media reports suggest the infection may have been caused by accidental exposure to extremely lethal pneumonic plague.

Pneumonic plague is a rare but often rapidly fatal disease that spreads via respiratory droplets from animals or people infected with the Yersinia pestis bacteria.

Few details about the incident have been verified, but the British Medical Journal (BMJ) reports that the young scientist, who worked at the Irkutsk Research Anti-Plague Institute of Siberia, Russia, died on October 1, two days after being admitted to the hospital with a diagnosis of pneumonia of “unknown origin.”

According to the BMJ report, Russia’s national public health agency said its authorities are responding with “anti-epidemic measures,” including ordering nearly 200 people to remain under observation, according to independent regional news outlet Liudi Baikala.

“We still have a lot to learn about this incident, but I think this was likely an unfortunate laboratory accident where protocols were not followed, leading to this very unfortunate outcome for this lab worker,” says Nicole Iovine, MD, chief hospital epidemiologist at the University of Florida Health in Gainesville and a clinical professor of infectious diseases and global medicine at the UF College of Medicine. “The plague is a very serious disease, but it's also a rare disease. So overall, I think the threat to the general population is very low, and it does not have pandemic potential.”

Pneumonic Plague Is Not Unheard of in the U.S.

U.S. health authorities document an average of seven human plague cases per year, making the illness rare but not unheard of stateside.

The specific type of plague depends on where the infection takes hold:

  • Bubonic plague affects the lymph nodes.
  • Pneumonic plague attacks the lungs.
  • Septicemic plague infects the blood.
  • Pharyngeal plague affects the throat.
Per the Centers for Disease Control and Prevention, most plague cases in the United States are bubonic, and occur in northern New Mexico and Arizona.

The bacterium responsible for plague is commonly spread by fleas. Humans typically contract bubonic plague after being bitten by an infected rodent flea or by handling an infected animal. When the bacteria enter the body through a flea bite, they tend to migrate to the lymph nodes.

In recent times, plague epidemics affecting larger populations have occurred in Africa, Asia, and South America. Cases are more likely to occur in areas with large wildlife populations that can sustain bacteria-carrying fleas, and where people live in conditions that bring them into close proximity with such animals.

Situation Is ‘Very Low’ Risk Outside Russia, WHO Says

While the U.S. State Department is closely monitoring the situation, the World Health Organization (WHO) has called the situation “very low” risk outside the country, according to PBS News.

Experts consider Yersinia pestis a potential biological weapon. Because the incident occurred in a Russian research lab, there are concerns that the Russian government could be covering up a program that poses a serious risk to global health, according to the Center for Infectious Disease Research and Policy.

Plague Risk Remains Low in the U.S.

If the Russian lab worker did, in fact, die from pneumonic plague, the risk to Americans is still very low, says Robert H. Hopkins, MD, medical director of the National Foundation for Infectious Diseases.

“Plague can be transmitted from person to person, but it is only spread by contact with saliva or respiratory secretions directly from the infected person,” says Dr. Hopkins. “The likelihood this will become a pandemic is very small. Viruses like influenza and COVID much more easily pass from person to person than the plague bacteria.”

Dr. Iovine adds that infected people usually become ill very quickly and tend to isolate soon after. “It’s really unlikely that somebody with pneumonic plague is going to be out and about in public, potentially spreading it to the population at large,” she says. “The real risk is to close contacts, family members, and possibly healthcare workers.”

People can lower plague risk by avoiding areas known to have rodents with infected fleas, and by being cautious around dogs or cats that may have been exposed to these fleas.

A young man in Arizona died in 2025 of pneumonic plague due to this kind of exposure, after close interaction with two infected cats.

Know the Symptoms of Plague and Get Treatment Fast

If you suspect you’ve been near a potential source of plague, be aware of these symptoms, per Cleveland Clinic:

  • Chills
  • Fever
  • Headaches and body aches
  • Weakness and fatigue
  • Dizziness
  • Nausea, vomiting, and diarrhea

When the infection is bubonic, it can cause painful, swollen lymph nodes, while septicemic cases can cause abdominal pain and bleeding from the nose and mouth, or under the skin. Pneumonic plague can cause shortness of breath, chest pain, cough, and bloody or watery mucus, and pharyngeal plague can cause sore throat.

Antibiotics are usually very effective at treating plague if the illness is diagnosed early.

EDITORIAL SOURCES
Everyday Health follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, board-certified medical experts, patients with lived experience, and information from top institutions.
Resources
  1. Soucheray S. Suspected Plague Incident Leaves 1 Dead, 200 Under Quarantine in Siberia. Center for Infectious Disease Research and Policy. October 5, 2026.
  2. How Plague Spreads. Centers for Disease Control and Prevention. May 15, 2024.
  3. Wise J. Russia Plague Outbreak After Reported Death of Lab Worker: What You Need to Know. The BMJ. October 5, 2026.
  4. Plague: Maps and Statistics. Centers for Disease Control and Prevention. March 25, 2025.
  5. Plague. Cleveland Clinic. January 5, 2026.
  6. Plague. World Health Organization. September 29, 2026.
  7. Keaten J et al. How Russia and the World Are Responding to a Possible Case of Pneumonic Plague after Lab Worker Death. PBS News. October 6, 2026.
  8. Wang CA et al. Notes from the Field: Fatal Pneumonic Plague — Coconino County, Arizona, July 2025. Centers for Disease Control and Prevention. October 1, 2026.

Tom Gavin

Fact-Checker

Tom Gavin joined Everyday Health as copy chief in 2022 after a lengthy stint as a freelance copy editor. He has a bachelor's degree in psychology from College of the Holy Cross.

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Don Rauf

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Don Rauf has been a freelance health writer for over 12 years and his writing has been featured in HealthDay, CBS News, WebMD, U.S. News & World Report, Mental Floss, United Press ...